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Kinase Inhibitor DiscoveryNotebook
CH-218 shows sub-100 nM CDK7 potency
Experiment logMaya ChenVersion 3
Dose-response for CH-218 confirms an IC50 of 38 nM against CDK7. Selectivity over CDK2 is 64×, the best in the lead series so far.
DatasetKinase Inhibitor IC50 PanelOpen
Format CSV576 rows4 columns
Numbers from a dataset. The embed links to the dataset itself.
Data Assistant
CH-218 is the most selective compound in this panel: 38 nM against CDK7, 2,432 nM against CDK2.
Based on:Your data1 tool call
AI text is labelled. Assistant answers name the assistant and the data they used.
2 comments
Provenance
- Version
- 3
- Recorded
- By
- Maya Chen
- SHA-256
- 4376 55dc 7010 2f038a9b e9ab b06a f9edd106 29a6 d984 13cdc7de c60b 8d81 e981
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